Thursday, November 5, 2009
MUTATIONS
In this post I question some of the
assumptions of both Darwinian evolutionists and intelligent designers.
Intelligent designers are not to be confused with creationists. Creationists are
people that refuse to consider any ideas or conjectures, no matter how they were
arrived at, that are in conflict with the account of creation as found in the
biblical Book of Genesis. Intelligent designers are people, often scientists,
who reject Darwinian evolution as an explanation for the origin and development
of life because they feel that it fails, as a theory, to explain the bewildering
complexity and coherence of life forms. Perhaps the population of creationists
is dwindling as more progress is made in biological research, but with the use
of modern instrumentation, including electron microscopes, X-ray crystallography
and DNA microarrays, and the fantastic complexity of life that is revealed at
it's most minute and 'simple' level, the ranks of intelligent designers, as
opposed to creationists, are swelling.
Just as people tend to confuse
and conflate creationists with intelligent designers, there is much confusion
and conflation regarding the theory of Darwinian evolution itself. There are
really, as microbiologist Michael Behe, the 'father' of intelligent design
explains, three separate yet related Darwinian notions. The first is the theory
of common descent which states that all life forms have evolved from the same
original ancestor. There is seemingly a lot of proof for this part of the
theory, including many similarities of structures and function in all life at
the molecular level and within phyla or kingdoms or species, a remarkable
similarity of structure and function at the level of visible organs and traits.
From the perspective of modern science, including intelligent designers, this is
powerful evidence for a common ancestor. And it does seem like a fairly
reasonable assumption: if we have hair and an ape has hair and a raccoon has
hair; then at some point in the very distant past, there was probably an
ancestor of all three of ours that had hair. As I say, intelligent designers
have no quarrel with this aspect of evolutionary theory, although I do, and will
discuss this later on.
A second notion of evolutionary theory is natural
selection, which is basically this: If there are a variety of species and a
variety of different individuals within a species, then those species and those
individuals that are more fit, that are better adapted to their environment,
will survive more readily than those individuals and species that are not as
well adapted. Over time the better adapted individuals will replace the more
poorly adapted ones and will dominate that species, and the better adapted
species will dominate other species. Natural selection, for the most part, is
also not really argued among intelligent designers. It is obviously true, but
perhaps, more complicated than originally thought. The qualities that make an
individual member of a species better adapted are often other than the obvious
qualities of stronger and faster. Sometimes species and individual members of
species survive because they are better able to float below the radar of
predators. Sometimes they are better able to cooperate among themselves to get
their needs met, and function better in groups. Sometimes their judgement is
better as to using safer paths to get their needs met. And so on. Also, as the
environment keeps changing, it favors one species over the other. As the weather
gets hotter then colder, then hotter, different species and different
individuals within species are favored. The same is true for cyclical changes in
humid vs. dry environments, warmer vs. colder ocean water, and many chemical
changes; more saline vs. less, more oxygenated vs. less, more carbonized vs.
less, etc. Once the basic conditions on this planet stabilized and the
atmosphere became oxygenated, all indications are that environmental changes
have been cyclical rather than linear. It's hard to imagine a linear
evolutionary path being naturally selected by cyclical changes in the
environment.
It should be noted that both of these first two aspects
of evolutionary theory, common descent and natural selection, have no power what
so ever to explain how anything originally got here or how anything gets more
complicated once it is here. The first part alludes to a common ancestor, but
from where and how did this ancestor arrive? The second deals with selection not
creation. Natural selection can cull from existing types, but how do those types
find their existence in the first place?
Let me just mention a word about
natural selection and its limitations. Selection, natural or otherwise, is just
that; a selection from existing types. If you eat at a restaurant, you select
different things on the menu. You do not create the menu. You are the diner, not
the chef. Now if, over time, no one selects certain dishes, and the chef or the
owner is throwing out this uneaten food every night, this will put a very strong
pressure on them to eliminate this dish from the menu. Also if, over time, not
only are certain dishes not selected, but the entire restaurant is not selected
and the customer base is dwindling, that will put pressure on the chef or the
owner to come up with some new dishes and, over time, either the menu will
change or the restaurant will disappear; but, again, while the selection process
may pressure the chef to create new dishes, the selectors (the customers) never
actually create these dishes. That is always the province of the chef or the
owner. And it should be noted that if the chef or the owner lack the creativity
and intelligence to come up with appealing new dishes or a new way of presenting
those dishes or some change that will make their restaurant more attractive to
customers, then the whole restaurant will dissappear. So, in terms of
restaurants at least, their survival is contingent on the intelligence and
creativity of chefs or owners to respond to the pressures of selection.
Selective pressures, by themselves, create nothing.
In the theory of
evolution, then, who is the chef? The only explanation for the creation of new
species, new forms, new body plans and for the increase in complexity of these
forms and plans in Darwinian evolution is through the avenue of blind,
accidental and fortuitous mutations. Although Darwin had no way of knowing it in
his day, these mutations take place, according to modern science, by an accident
in the genetic copying of genes during the process of replication. Genetic
sequences are long strings of nucleic acid molecules, or nucleotides, which are
coded for specific amino acids. In our cells, a long series of coded nucleic
acids is transcribed within the nucleus onto an RNA molecule which transports
this code outside of the nucleus of the cell to a ribosome where it is
translated to a corresponding long series of amino acids that, when linked
together and folded, form a protein. A genetic copying accident can result in a
change in a nucleic acid, which can result in a change in the amino acid that
that nucleic acid is coded for. These accidental changes are very rare (about
one 'mistake' in one hundred million copies) and are almost always either
deleterious, and damage the mechanisms of the cell and the workings of the body;
or neutral and have no visible effect at the level of either the cell or the
organism; still, extremely rarely, there is a very, very rare mutation that,
according to the theory, causes an improvement in the workings of the cell, that
increases the survivability of the cell and the organism of which this cell is a
part; and future generations will favor this positive change and in this way the
organism will improve and eventually, over a very, very long time, undergo
radical change.
This part, the random mutation part, is the one that most
bothers intelligent designers. It just does not seem, to intelligent designers,
to be a process that occurs frequently enough to deliver anything like the
amazing variety and complexity of life forms that we find today. So the math
does not work. Also you would expect from this sort of change a very gradual yet
very consistent change among organisms so that not only would every organism be
linked in very gradual clear steps to every other organism, but that these
changes should have taken place at consistent, regular and frequent intervals in
our history. Yet, simple observation tells us that there are no such links. Each
mammal is very much a mammal and not to be confused with a bird or an insect;
just as every insect is very much an insect and not to be confused with a
reptile or a fish. Not just on the outside of their bodies, but each has a
completely distinctive internal form of organization; there is clearly a
mammalian way of organizing internal organs, a mammalian kind of digestive,
reproductive and nervous system, and there are very clear and distinct avian and
insectivore forms of internal organization. Also, historically, there is
absolutely no evidence of this gradual, relentless change of species. In fact,
quite the opposite is the case. All evidence points to the first cells appearing
suddenly, about four billion years ago, at the moment that conditions on this
planet supported their survival (when the surface of the Earth became cool
enough to have non-boiling water). There are no traces of organic tidepools (the
so-called pre-biotic soup), no traces of any organic material at all prior to
the appearance of these photosynthetic, metabolizing, digesting, growing and
environment sensing bacteria. Then, for two billion years after that, fully half
of the entire history of life on Earth, there was absolutely no evolutionary
change, in the sense of life forms changing their basic structure or complexity.
Four billion years ago there were bacteria and only bacteria; and two billion
years later there were bacteria and only bacteria. Now among these bacteria
there were all sorts of adaptations, so that bacteria were able to thrive in all
kinds of environmental conditions: extreme heat, extreme cold, high acid, high
base, little water, etc. If by evolution one means adaptation, then, yes
evolution was taking place. But what we commonly think of as evolution is the
evolving of one species from another; of a change of shape, body plan and basic
structure. In that sense of evolutionary change, for two billion years there was
none.
While we're on the subject, it's important to distinguish between
evolution and adaptation. If you follow traditional evolutionary thinking, these
processes of change, which would have taken many, many centuries where life
forms were in a kind of awkward transition; where new organs or forms were
gradually taking shape, but not yet functional as they awaited the next in a
series of almost impossibly rare mutations to complete their formation; these
transitional forms would not be adaptive at all. In fact, they would be the very
opposite of adaptive. They would be using a lot of metabolized energy to sustain
equipment that was in some stage of incompletion and not yet functional. That
would put them at a clear competitive disadvantage to those creatures who were
not taking this terrifying evolutinary journey, and whose every organ and every
calorie of metabolized energy was being used to assist in their present time
survival. Clearly the most adaptive of all creatures is the single celled
bacteria. They can survive in every nook and cranny of this planet and they
outnumber us more complicated creatures by the trillions. If any creatures
actually left the adaptive comfort of being bacteria to venture into this almost
endless process of accumulated fortuitous mutations, they would be risking their
survival, not securing it. Evolution, then, is the opposite of
adaptation.
Much of the confusion around evolution and the vehemence on
both sides of the argument, stems from the failure to distinguish between two
aspects of a living organism. A living organism both produces chemicals and
builds the factory where these chemicals are produced. One mutation, or a
change of one amino acid, in the chemicals that a body produces to protect
itself and help it digest, can make a marked improvement. One, or two sequential
mutations, can confer protection from certain pathogens and allow the members of
a certain species that have that mutation to thrive and replace the members of
the same species that are vulnerable to that pathogen. The same is true with
digestive fluids. One or two sequential amino acid changes may allow an
individual member of a species to digest and use the energy of a food source
that is toxic or unusable to the other members. Again, that mutation, that one
or two sequence amino acid change, would confer a distinct advantage in a
particular environment, and the individuals that had that mutational advantage
would thrive and dominate the population of the species that were exposed to
that pathogen or that food source.
There is no argument in terms of
mutations being able to alter body chemicals and chemically confer advantages
and disadvantages. (Although there is a strong disagreement about how this
amazing system that requires genetic replication, transcription and translation,
metabolism and digestion, and immune system protection from pathogens, and was
brilliant enough to have variation within species and include these occasional
mutations to enhance the survivability of a species; how all of this technical
brilliance arrived here in the first place. Yes, there is a very big difference,
not about the functioning, but about the origin of this whole system.)
The bigger area of disagreement lies in the area of mutation of the
genes involved in the construction of the chemical factory itself. It is in the
construction of bodies and their biological systems that we enter a world of
absolutely fantastic complexity. As opposed to the manufacture of enzymes,
bodies are not created with the simplicity of one genetic sequence doing this,
and one genetic sequence doing that. Genes involved in the construction of
bodies are fired in enormously complex sequences, and each gene sequence, which,
really, produces one building material used in the construction of this factory,
is combined with other gene sequences to make amalgams of other proteins for
other materials, and the same gene is used in many different parts and at many
different times in the construction of the body. Everything is amazingly
intertwined, and does not just depend on the genome, but on the firing patterns
that initiate the process of transcription and translation, of protein
synthesis.
Let's think about the power of these firing patterns for a
minute. In our own body, the same genome, depending on which genes are fired,
produces our fetal body, our child body, our adult body and our senior body.
With no change in the genome, different firing patterns produce our brain cells,
nerve cells, blood cells and muscle cells. The same genome produces both the
caterpillar and the butterfly. And the breathtaking biological journey of the
butterfly is merely a walk to the corner store when compared to the biological
oddysey of some creatures like the liver fluke. Follow the journey of the liver
fluke with, of course, one unchanging genome, as it is described by molecular
biologist Michael Denton:
" The adult lives in the intestine of a
sheep. After the eggs are laid they pass with the faeces onto the ground. The
eggs hatch, giving rise to small ciliated larvae which can swim about in water.
If the larvae are lucky they find a pond snail: they must do this to survive,
for the snail is the vehicle for the next stage in the life of the liver fluke.
Having found a snail the larvae finds its way into the pulmonary chamber or
lung. Here it loses its cilia and its size increases. At this stage it is known
as a sporocyst. While in this condition it buds off germinal cells into its body
cavity which develop into a second type of larvae known as rediae. These are
oval in shape, possessing a mouth and stomach and a pair of protuberances which
they use to move about. The rediae eventually leave the sporocyst, entering the
tissue of the snail, after which they develop into yet another larval form known
as cercariae which appear superficially to resemble a tadpole. Using their long
tails these tadpole-like larvae work their way through and eventually out of the
snail and onto blades of grass, where each larva sheds its tail and encases
itself in a sheath. Eventually they are eaten by a sheep Inside the sheep they
find their way to the liver where they develop sexual organs and mature into the
adult state. They finally leave the sheep's liver and migrate to the intestine
where they mate and so complete their extraordinary life cycle."
This entire oddysey, I remind you, is done with no change in the
genetic make up of the liver fluke. At this juncture, you must wonder if there
is not some level of organization that is higher than the genome. We have been
taught to look at the genome as an ultimate cause. But is it possible that the
genome, itself, could be a result; a result of something else, a higher order of
organization than the genes themselves?
I had an interesting
correspondance with a molecular biologist recently. I will respect his request
that I not publish any of his e-mails on this blog, but I do want to summarize
one part of our communication. We were discussing gene transcription. To begin
the process of protein synthesis, the desired strand of genetic code (nucleic
acids, or nucleotides, that codes for that particular protein) must be
transcribed onto an mRNA molecule which then transports this message to another
part of the cell where it is translated into a corresponding chain of amino
acids and then into a protein. I was wondering how the molecules that form the
mRNA find that exact spot in the DNA (three billion nucleotides long in the case
of human DNA) which is coded for the desired protein. He said, basically, that
science has not yet figured out all the mechanisms, but for one thing, the DNA
is folded differently in different cells, so that the pieces of code that are
frequently used in a particular cell (like the codes for adrenal cortical
hormone in adrenal gland cells and the codes for manufacturing saliva in
salivary gland cells, etc.) are always located on the most exposed surface of
the nucleosome so the molecules do not have to search through anywhere near
three billion nucleic acid molecules. Here again is another indication of a
higher order of organization than the genome itself. If there is a fantastically
complex pattern of gene foldings, so that genes in different cells are folded
differently, exposing the codes most used by that particular cell to the outside
surface of the nucleosome; isn't this another powerful suggestion that there is
a level of organization higher than the genome itself? How could the same genome
determine a whole variety of different folding patterns for itself?
I
told him that I thought all these microbiological processes were guided. He very
adamantly insisted that they were not; that he was certain that there were
mechanisms at every step, although many of these mechanisms had not yet been
discovered, that explain how all these processes are accomplished within the
cell according to known laws of chemistry and physics without any guidance. But
I have no argument with mechanisms and understand that all these reactions must
occur following inviolable physical laws. Guidance occurs not by violating
physical laws but by martialing the energy to overcome physical forces. For
instance if we humans guide anything, and we do that all the time, we do it not
by violating physical laws but by mechanically overcoming them to get what we
want. Let me explain:
One of the ways that scientists use to describe
how proteins come together, or how a molecule of a protein will find the
corresponding molecule of a nucleic acid, is by using the image of a lock and
key. Each protein molecule has a complex three dimensional shape. Proteins bind
when, among other things, their shapes correspond with each other and 'fit,'
like a key fitting into a lock.
Let's suppose that a group of aliens
arrived on this planet that just did not get human beings at all and thought
that we were completely and totally automated machines. Now there are some
scientists who claim to think that way also. Steve Pinker and Richard
Dawkins,for instance, who claim to be complete materialists, who claim that we
and all of life is entirely mechanical. The thing is that although they talk
that talk, they never walk that walk. Regardless of what they say, they still
treat people as living beings, as creatures capable of will (who do what they
want to do) and creatures capable of experiencing things. Even the worst slave
drivers or Nazi concentration camp guards, realized that the people they were
torturing and coercing had will and were capable of experience. Even if you want
to, you cannot torture a rock. Torture implies the capacity of experience in the
tortured. To get people to perform onerous labor for no reward, the slave driver
knows he must coerce them. That means that he must make the punishment for
refusing to do what the slave driver wants much worse than the actual doing it.
The slave does what he is asked, not because he has no will or desires, but
because he wants the severe punishment for not doing it less than he wants the
pain and discomfort of doing it. You do not have to coerce a machine to do its
work. You just turn it on.
So, aside from these intellectuals who
theorize one way but behave in another, let's imagine that there were aliens,
the Gonks, who landed here and really believed that we were not living beings
with will and the capacity to experience, but that we were merely machines. Now
the Gonks did not come to torture us (again, how could you torture a machine).
They were just here to study us. And one of the things they studied was our
doors, and how we got in and out of them. To that end they did comprehensive
studies (they were as scientifically advanced as they were socially retarded,
and could detect every minute physical detail with their non-invasive scientific
instruments, but could notice nothing about mood, feeling or behavior with their
naked eyes.) So they saw that when a human machine had to get through a door it
focussed its two round electric cameras (eyes) on the door which sent a signal
to its two stilt appendages (legs) which started propelling the machine toward
the door (walking). To accomplish this on a cellular level they saw that a
certain amount of metabolic energy was used to fire many thousands of neurons,
setting off many thousands of chains of electrical impulses, and many expansions
and contractions of leg and foot muscles. Then, as the door was approached a
small brittle instrument (key) was removed by one of the hanging upper
appendages (arms) from a sac located just below the waist (pocket). With the aid
of the two electric cameras the brittle instrument was brought to the precise
spot where there was a slit in the outside surface of the door (lock). This
again was accomplished by many contractions and expansions of muscles at the
part of this appendage closest to the trunk (biceps and triceps) but especially
with the smaller appendages that descended at the end of the larger one
(fingers). This small brittle instrument was then pushed into this slit opening
and every shape of the brittle instrument matched, exactly the shapes of the
cavity it was entering. More energy was applied through those lower appendages
to turn the instrument which was connected to a horizontal rod. As one of the
upper appendages turned the instrument the rod was released, and with the help
of the cameras, the other upper appendage was moved to a round protuberance
below the slit (knob) which was turned by the contraction of several muscles in
these descending appendages. Then, when all the obstacles to the door opening
were removed, the door then opened and the machine continued through the door on
its two stilts and accessed its fuel (food). The Gonks continued these
observations and calculations until they were satisfied that everything, in
terms of the amount of energy metabolized, the balancing of electrical charges
and the skeletal and muscular mechanics fit their physical, chemical and
thermo-dynamic formulas.
So, you see, if you study our behavior
'scientifically' you would also see no guidance. That is because WE, the part of
us that wills, that wants to do things and that experiences things, is not
visible. As fellow human beings we can recognize what is willful in each other
and, to some degree, what each other is experiencing, by the way those
experiences and that will affects our body and our behavior. So we know that
someone opens a door because they "want" to go inside, and that wanting is what
martials all these microscopic and macroscopic activities that the Gonks so
diligently studied. But we cannot observe our wanting, or our objectives, or our
purposes directly. All our willful activity is guided, but we can only observe
directly the physical, electrical and chemical results of that guidance.
The same thing holds true, of course, for our man-made machines. If the
Gonks chose to study any of our machines, they would see that they too, complied
with all their formulas. Man-made machines are obviously guided and purposeful,
but, as with our willful activity, those purposes cannot be directly observed.
The purpose of the machine and the idea of the machine first existed in the mind
of the inventor before it was committed to a plan on paper or on a computer
screen and before that inventor martialed the forces and the materials to
manifest his idea on the physical plane. Steve Pinker babbles about 'killing the
ghost in the machine,' so why can't he tell me the weight of the 'idea' that
gave birth to the machine and the measurements of the will that martialed the
forces and the materials to build it?
If all our willful activity and
our machines are obviously guided, what about our involuntary, non-willful
activity: things like growth, replication, digestion, circulation, etc. My point
is that whether or not all these activities are guided, the fact that you cannot
directly observe that guidance, and the fact that all these activities conform
with the basic laws of physics and chemistry, have no bearing on whether they
are guided or not.
Let's get back to mutations. Putting aside the
very serious considerations that there doesn't seem to be any way that enough of
these extremely rare fortuitous mutations could have taken place to deliver the
astonishing complexity and variety of current life forms and that historical
evidence (the fossil record) leads us in a very different direction, is there
something else; a very basic problem in our understanding of the construction of
living bodies and our understanding of the gene itself that would make such an
accidental, mutational development logically impossible? It seems to me that
there are two logical problems with our understanding of mutations; one of which
you may have heard of before and one of which is brand new to this post (at
least I hope it is).
The first logical objection to mutations as the
pathway for evolutionary change and development is the problem of coherent
complexity. If we want to talk about the body as a machine, it is an enormously
complex one, certainly far beyond the complexity of any man made machine. But if
we take a comparatively simple machine, like say a pocket watch; all the various
parts of the watch are coherent, in that they are all precisely designed to fit
with each other in a way that delivers the desired result (accurate time). What
possible accidental change (or even purposeful change, for that matter) in one
individual part of the watch could bring about any improvement? The first thing
that would happen if you change the shape of any part is that the watch would
stop. It is possible that an identically shaped part of a different material
could bring about an improvement(say a more durable metal part replacing a
plastic part) but proteins don't work that way. All proteins are three
dimensional. Any change in any amino acid part of a protein creates a change in
shape. If that protein is added to a system of great coherent complexity, then
the system, rather than improving, breaks down. It is impossible to imagine a
watch changing step by step into a better watch, or a television changing step
by step into a better television. Any major improvement may borrow some
ideas from earlier models, but the actual construction would have to
start from the beginning and not be tagged on at the end. Here are Michael
Behe's words:
Some systems seem very difficult to form by such
successive modificationsI call them irreducibly complex. An everyday example of
an irreducibly complex system is the humble mousetrap. It consists of (1) a flat
wooden platform or base; (2) a metal hammer, which crushes the mouse; (3) a
spring with extended ends to power the hammer; (4) a catch that releases the
spring; and (5) a metal bar that connects to the catch and holds the hammer
back. You can’t catch a mouse with just a platform, then add a spring and catch
a few more mice, then add a holding bar and catch a few more. All the pieces
have to be in place before you catch any mice.
Natural selection can
only choose among systems that are already working so irreducibly complex
biological systems pose a powerful challenge to Darwinian theory.Irreducibly
complex systems appear very unlikely to be produced by numerous, successive,
slight modifications of prior systems, because any precursor that was missing a
crucial part could not function. Natural selection can only choose among systems
that are already working, so the existence in nature of irreducibly complex
biological systems poses a powerful challenge to Darwinian theory. We frequently
observe such systems in cell organelles, in which the removal of one element
would cause the whole system to cease functioning. The flagella of bacteria are
a good example. They are outboard motors that bacterial cells can use for
self-propulsion. They have a long, whiplike propeller that is rotated by a
molecular motor. The propeller is attached to the motor by a universal joint.
The motor is held in place by proteins that act as a stator. Other proteins act
as bushing material to allow the driveshaft to penetrate the bacterial membrane.
Dozens of different kinds of proteins are necessary for a working flagellum. In
the absence of almost any of them, the flagellum does not work or cannot even be
built by the cell.
Molecular machines are designed. Biochemistry textbooks
and journal articles describe the workings of some of the many living molecular
machines within our cells, but they offer very little information about how
these systems supposedly evolved by natural selection. Many scientists frankly
admit their bewilderment about how they may have originated, but refuse to
entertain the obvious hypothesis: that perhaps molecular machines appear to look
designed because they really are designed.
Advances in science provide
new reasons for recognizing design.I am hopeful that the scientific community
will eventually admit the possibility of intelligent design, even if that
acceptance is discreet and muted. My reason for optimism is the advance of
science itself, which almost every day uncovers new intricacies in nature, fresh
reasons for recognizing the design inherent in life and the
universe.**
Now this was excerpted from an article that appeared in
Natural History Magazine, a magazine with a clear anti-design bias. Therefore to
refute Behe, they must have searched carefully for the best rebuttal to his
argument that they could find. Here's what they came up with, excerpted from a
rebuttal argument to Behe by biologist Kenneth R. Miller:
Parts of a
supposedly irreducibly complex machine may have different, but still useful,
functions. Ironically, Behe’s own example, the mousetrap, shows what’s wrong
with this idea. Take away two parts (the catch and the metal bar), and you may
not have a mousetrap but you do have a three-part machine that makes a fully
functional tie clip or paper clip. Take away the spring, and you have a two-part
key chain. The catch of some mousetraps could be used as a fishhook, and the
wooden base as a paperweight; useful applications of other parts include
everything from toothpicks to nutcrackers and clipboard holders. The point,
which science has long understood, is that bits and pieces of supposedly
irreducibly complex machines may have different but still useful functions.
Evolution produces complex biochemical machines.Behe’s contention that
each and every piece of a machine, mechanical or biochemical, must be assembled
in its final form before anything useful can emerge is just plain wrong.
Evolution produces complex biochemical machines by copying, modifying, and
combining proteins previously used for other functions. Looking for examples?
The systems in Behe’s essay will do just fine.
Natural selection favors
an organism’s parts for different functions.He writes that in the absence of
“almost any” of its parts, the bacterial flagellum “does not work.” But guess
what? A small group of proteins from the flagellum does work without the rest of
the machine it’s used by many bacteria as a device for injecting poisons into
other cells. Although the function performed by this small part when working
alone is different, it nonetheless can be favored by natural
selection.
Is that the refutation of Behe? This silliness misses
Behe's point entirely. Yes, someone could use my stomach for a wine sac; could
use my intestines to tie down luggage to the roof of a car, and play castinets
with my teeth. That someone would, of course, not be me, because I, no longer
having a stomach or intestines would be long dead. Behe's whole point is that
there must be a continuous biological function. If any organism along the
way uses its digestive system to play music, tie luggage or for any other
purpose, what, in the world are they going to digest with? The point is that the
digestive system, or the locomotion system, or the circulation system has to
change increment by increment while still being a working digestive, locomotion
or circulating system. How was this organism metabolizing before it 'learned' to
metabolize? How was it eliminating before it 'learned' to eliminate? Unlike when
we remodel our home and move out to a hotel for a month while new plumbing and
new wiring is installed; biologically we couldn't have moved into a primordial
hotel for fifty million years while our body was developing new nervous and
digestive systems. Moving out is what we call death, the end of the line,
biologically, evolutionarily, or otherwise. However long these evolutionary
processes were supposed to take, all the basic biological processes must have
been continuously functional throughout the entire process; and not only
functional, but functional at a level of efficiency that enabled them to compete
with other organisms that were not going through the radical upheaval of a
process of evolution.
The second logical objection to mutations as the
engine of structural changes in living bodies is actually the thesis of this
post. (Were you wondering when I was going to get around to the thesis?) While
intelligent designers make convincing arguments of math, history and coherent
complexity, their assumption is always that if there were a way to explain how
that many coherent mutations could have accumulated (which there is not) then
that would convince us of the validity of Darwinian evolution. These arguments
still miss the mark. The visible genome, as we see it and measure it, cannot, by
itself, account for the entire construction of a living body, so mutations, or
changes in the genome, cannot account, by themselves, for changes in that
construction.
To make my point I would like you to think about the
construction of man-made machines (by the way, if there is a reasonable gender
neutral way of saying 'man-made' please let me know. I've come up with a few,
but they all sound ridiculous.) How do you create a machine? Machines begin,
like all man-made things begin, with a desire. You want to be able to do
something, or accomplish something that you are not able to do. This unsatisfied
desire creates a kind of stirring, a restlessness. You think about what you want
and the obstacles that you must overcome to get what you want. Out of this
restlessness comes the idea for a machine. Once you commit to actually
manifesting this machine on a physical plain, you inevitably encounter other
obstacles which require further ideas to overcome them. So the manifestation of
a machine is usually the result of several 'hmmmm' moments as you run into
obstacles, followed by several 'aha' moments as you come up with ideas to
overcome these obstacles.
Beyond the kind of energy that you choose to
operate your machine (mechanical, electrical, thermal, etc.)the idea for a
machine consists of two parts. The first part is choosing or, if necessary,
inventing, the materials that you need that have the right characteristics (the
right strength or suppleness or rigidity or porousness, etc.) and the second is
the shape that these materials must be formed into to direct the energy to its
desired result. So the idea consists of materials and shapes. And finally you
need a plan. The plan is the actual logistics of accumulating the materials you
need in the right amounts and the right order to get the job done, and then the
method of shaping these materials to achieve the exact contours that you need to
get the desired results.
At this point I wanted to show you a video of
the construction of a large building using time lapse photography. Please excuse
my technical ineptness, but you will just have to imagine such a video. You have
probably seen one at sometime. You see bulldozers excavating a hole in the
ground; cranes arriving, and the building growing from the ground up, a process
that probably took many months, if not years, consolidated to the span of a
minute or two.So please make believe that you just watched such a video.
Thanks.
Everything that is being constructed is the physicalization of
first an idea, which consists of the materials and the shape of the building,
and further a plan to get these materials in the right order to the job site and
to shape these various materials to the exact size as indicated by the plan. Of
course, you cannot see the plan on the video, but obviously the workers and the
foremen were following these plans at every step of the construction. And, of
course, the idea, itself, can never be directly observed. It existed solely in
the mind of the architect before it was committed to paper or to a computer
screen. I don't want to belabor the point, but I do have to emphasize that the
building could not be built without both a method for delivering the right
materials, in the right order, and a specific design of the shape of the
building with a means of achieving that shape.
So if you go back to the
video (that you were supposed to have just seen), you see that bulldozers
arrived first to dig a hole for the foundation and then cranes arrived to move
heavy materials into place. If the cranes got there before the bulldozers that
would create an inefficient logistical nightmare. The cement must come before
the iron girders which must come before the dry wall which must come before the
office furniture, etc. Everything must arrive and leave the construction area in
sequence. Suppliers must be notified in time so that they can manufacture the
materials and deliver them to the site when they are needed. And everything has
to take place according to not just a plan of sequence but a plan of shape. The
bulldoze drivers need to know how big and how deep to make the hole. The steel
workers need to know the outer dimensions of the building, etc. The materials
and the shape that these materials take is dictated by the plan which is the
first stage of physicalization of a non-physical idea in the mind of the
architect.
Biological machines also consist of various materials and
shapes. Biological machines are necessarily more complicated than man made
machines because a living body not only constructs these various machines, but
also manufactures the materials out of which these machines are made. There are
macroscopic machines that we are all familiar with, like hearts and kidneys and
livers and lungs and there are microscopic machines within individual cells. A
microscopic cellular machine that has been study intesively over the last
several years is the flagellum. A flagellum is a kind of outboard motor which
allows a bacterium to move about in a liquid medium. Here is an excerpt of
Michael Behe's description of the construction of the flagellum from his book,
The Edge of Evolution:
Just as the outboard motor of a motorboat in
our everyday world consists of a large number of parts (propeller, spark plugs,
and so on), so does the molecular outboard motor. The flagellum has dozens of
protein parts that do the particular jobs necessary for the complex system to
work. Those dozens of proteins are coded by dozens of genes in a bacterial cell.
The genes are grouped into fourteen bunches called "operons." Next to each
operon in the DNA are control signals. The control signals themselves fall into
three categories we'll call class 1, class 2, and class 3. The genes for
proteins that have to be made first in the construction process have class 1
control signals, those genes that go second have class 2 signals, and so on.
Most of the time, a bacterial cell isn't building a flagellum, because
it already has one. However, after cell division a new cell has to start the
construction program. To begin, the DNA control regions for class 1 genes
mechanically "sense" that the time has come and switch on class 1 genes. There
is just one operon in class 1, which contains just two genes. The genes code for
two protein chains, which, like the alpha and beta chains of hemoglobin, stick
to each other to make a single functioning protein complex. That protein is
neither a part of the flagellum nor a part of the construction machinery.
Rather, it's akin to the foreman of a project, who has to tell the other workers
what to do. Let's call it the "boss" protein.
The boss protein binds
specifically to the DNA control regions of the seven class 2 operons,
mechanically turning them on. Class 2 genes code for the proteins that make up
the foundation of the flagellum (plus some helper proteins), just as you'd
expect in bottom up construction. One class 2 gene, however, isn't part of the
foundation. It's another control protein. Let's call it the "subboss" protein.
The subboss protein binds to the DNA control region of class 3 genes, which
comprise proteins that make the outer parts of the flagellum. So each class of
genes contains the gene for a protein that will turn on the next class.
But that's not all. Clever as that part is, the control system is much
more finely tuned than just the cascading control proteins. For years
researchers knew that if the genes for any of a score of protein parts in class
2-the ones that made up the foundation of the flagellum-were experimentally
broken in the lab, the genes for the outer parts of the flagellum would remain
switched off. But how could so many genes all control later construction?
Class 3 contains a gene for a protein that binds tightly to the subbboss
protein, inactivating it. Let's call that the "checkpoint" protein. Why turn on
the sub boss only to immediately inactivate it with the checkpoint protein?
Later in the construction project, a clever maneuver gets rid of the checkpoint
protein. The flagellum not only is an elegant outboard motor, but also contains
a complex pump in its foundation, which actively extrudes class 3 protein parts
to form the outer portion of the structure.
Here's the elegant trick.
When the pump in the foundation of the flagellum is completed and running, one
of the first proteins to be extruded is the checkpoint protein. Getting rid of
the checkpoint protein releases the subboss protein to bind to the control
regions of class 3 operons, switching on the genes for the outer portion of the
flagellum. So the completion of the first part of the flagellum is directly
linked to the switching on of the genes to make the final parts of the
flagellum.
In just the past few years a group of Israeli scientists has
developed clever new laboratory techniques to analyze in even finer detail the
control exerted by DNA control elements on the construction of the flagellum. By
successively joining the control elements to the gene for a protein that can be
detected by its fluorescence, the scientists showed that, even within classes 2
and 3, the control elements switch the genes on in the order that they are
needed for construction. Within class 2, the genes needed for the bottom of the
foundation are switched on before the genes for the top of the foundation, and
within class 3, genes for the bottom of the top are activated before genes for
the top of the top.
The same group of scientists has examined DNA control
elements for other cellular systems and discovered similar elegance there. When
they studied cellular biochemical pathways for making amino acids, they
discovered what is called "just-in-time" organnization, where a protein is made
as close to the time it's needed as possible:
Mathematical analysis
suggests that this "just-in-time" transcription program is optimal under
constraints of rapidly reaching a production goal with minimal total enzyme
production. Our findings sugggest that metabolic regulation networks are
designed to generate precision promoter timing and activity programs that can be
understood using the engineering principles of production pipelines.
What does all this jargon mean? Simply put, the more closely we examine
the cell, the more elegant and sophisticated we discover it to be. Complex,
functional structures such as the cilium(tiny hairlike organelles that can help
a single celled creature move through a liquid medium, or help larger creatures
move material through internal ducts) and flagelllum are just the beginning.
They demand intricate construction machinery and control programs to build them.
Without those suppport systems, the final structures wouldn't be possible. The
bacterial flagellum contains several dozen protein parts. The cilium, which so
far has resisted investigation of its DNA control program, has several hundred.
There is every reason to think that the control of its construction will have to
be much more intricate than that of the flagellum.
Control of
construction projects and other activities in the cell is difficult for
scientists to investigate, because "control" is not a physical object like a
particular molecule that can be isolated in a test tube. It's a matter of timing
and arrangement. The upshot is that even now in the twenty-first century-more
than fifty years after the double helical shape of DNA was discovered by Watson
and Crick, and decades after the first X-ray crystal structures of proteins were
elucidated-science is still discovering fundamental new mechanisms by which the
operation of the cell is controlled.
Recently-some sixty-five years
after George Beadle and Edward Tatum proposed the classic definition of a gene
as a region of DNA that codes for an enzyme-an issue of the journal Nature ran a
feature with the remarkable title "What Is a Gene?" The gist of the article was
that the control systems that affect when, where, and how much of a particular
protein is made are becoming so complex, and their distribution in the DNA so
widespread, that the very concept of a "gene" as a discrete region of DNA is no
longer adequate. Marvels the writer, "The picture these studies paint is one of
mind-boggling complexity."
The discovery of 'control' elements in
the DNA (operons, hox genes, realisator genes, gap genes, pair-rules genes,
etc.) supposedly make the creation of new biological structures through
accidental mutations more feasible,since the mutation of just a few 'control'
genes can alter the firing and replication patterns of many sub-genes; but
consider these words by molecular biologist Jonathon Wells:
"Natural
selection works only within established species.Darwin’s finches and many other
organisms provide evidence that natural selection can modify existing features
but only within established species. Breeders of domestic plants and animals
have been doing the same thing with artificial selection for centuries. But
where is the evidence that selection produces new features in new species?
Major evolutionary changes require anatomical as well as biochemical
changes.New features require new variations. In the modern version of Darwin’s
theory, these come from DNA mutations. Most DNA mutations are harmful and are
thus eliminated by natural selection. A few, however, are advantageous such as
mutations that increase antibiotic resistance in bacteria and pesticide
resistance in plants and animals. Antibiotic and pesticide resistance are often
cited as evidence that DNA mutations provide the raw materials for evolution,
but they affect only chemical processes. Major evolutionary changes would
require mutations that produce advantageous anatomical changes as well.
The four-winged fruit fly is an....“icon of evolution." Normal fruit
flies have two wings and two “balancers” tiny structures behind the wings that
help stabilize the insect in flight. In the 1970s, geneticists discovered that a
combination of three mutations in a single gene produces flies in which the
balancers develop into normal-looking wings. The resulting four-winged fruit fly
is sometimes used to illustrate how mutations can produce the sorts of
anatomical changes that Darwin’s theory needs.
This fly does not provide
evidence for evolution. The extra wings are not new structures, only
duplications of existing ones. Furthermore, the extra wings lack muscles and are
therefore worse than useless. The four-winged fruit fly is severely handicapped
like a small plane with extra wings dangling from its tail. As is the case
with all other anatomical mutations studied so far, those in the four-winged
fruit fly cannot provide raw materials for evolution."
How could
only three mutations in a single gene change the balancers into normal 'looking'
wings? Because these genes are part of a whole series of 'control' genes.
Control genes, like hox genes, realisator genes, gap genes and pair-rules genes
are genes that, once fired, signal the firing of a whole series of other genes
which results in the manufacture of a whole series of proteins. These control
genes have supposedly given fresh new evidence of how accidental mutations could
create new anatomical structures leading to brand new organisms. But as Weller
points out they do nothing more than rearrange existing structures, and in the
case of mutations of these genes, lead, not to an advancement, but to a horrible
deformity in which a poor organism has 'extra' structures but not all the other
connections (musculature, nerve connections, brain connections, adjustments in
support mechanisms and equilibrium) to make these extra structures functional.
What is becoming increasingly clear is that an organism is not an accidental
chance amalgam of individual genes, but a functional whole and any major change
in one area requires changes and adjustments throughout.
Going back to
the example of building construction, these regulator genes act as supply agents
for construction materials. If I were in charge of the construction of a
building, there are many suppliers that I would have to call in the proper
sequence and with the proper timing so that all the materials I would need would
arrive at the right time at the construction site. Suppose there was a supply
agent for building foundations. In other words, all I would have to do is
contact him and he, in turn, would see to it that all the bulldozers, the cement
mixers, the gravel, the re-inforcing bars, the lumber for the wooden cement
troughs, in other words everything that was needed for the foundation and in the
proper amounts, would be there at the construction site at the exact right time
that they were needed. And, perhaps, going one better than that, suppose when
that foundation supply agent was nearing the end of his check list, that he
would contact the wall supply agent, who, in turn, would make sure that all the
supplies necessary for the walls would arrive in sequence, and he, in turn,
toward the end of his work would contact the roofing supply agent. In this way,
with just one initial signal, my call to the first supply agent, the entire
sequence of needed materials for the first excavation all the way to the last
interior decoration would be guaranteed to arrive when and where they are
needed. Please notice that all of this still says nothing about the actual
constructing, the actual shaping and design of the building. For that I need
builders, and even if I had automated builders, they would still need to have a
plan, a design to follow so that all these materials could be fashioned into the
required shape to make the entire building work.
My point is that as
complicated as the manufacture of proteins and their timing and their delivery
to the exact construction sites are, all of that still says nothing about
how these proteins are shaped into the precise shapes that allow elegant
structures like the flagellum to function. As was said earlier in discussing the
video of the building construction, we need both the proper materials, their
delivery to the proper construction sites and, of course, the plan from which
the building is shaped. Where is the plan that determines not the materials, but
the shape of biological machines? Now don't confuse the shapes of the protein
molecules themselves with the contours of whatever it is that the protein
molecules are building. Protein molecules can bind with other protein molecules
to make amalgams of proteins, which have a very specific and unique shape, but
these are only the building blocks of biological construction. They no more
determine the shapes and contours of organs and organelles than the shape of
bricks determines the shape of brick houses, or the shape of grains of sand
determines the shape of sand castles. The analogy of Lego-pieces is often used
to illustrate in a simple way how proteins inter-lock. But if the inter-locking
mechanism of the Lego toy were only capable of creating one shape, how many Lego
games would be sold? The whole point of the Lego game is that with a few hundred
identically shaped pieces, with the same inter-locking system, one can create
many, many shapes. How many more varieties of shapes would be possible with
identical protein molecules that number not in the hundreds but in the thousands
and millions and billions? And it is the shape as much or more than the material
that creates the functionality of any machine, man made or biological.
Let's go back to Michael Behe's words. In his fairly detailed
description of the construction of both the cilium and the flagellum, there is
not a word of explanation regarding shape. All of Behe's description regards how
the genetic sequencing determines how the various proteins arrive at the
construction site in the proper amounts and in the proper order. The flagellum
construction begins with a base of three rings. Each of these rings is composed
of different proteins, and each has about twenty-six copies of their particular
protein. But why a ring? Why not a line, or an oval, or a squiggle, or a
rectangle, all of which shapes could be achieved with any of these proteins? The
flagellum would not work with any other shape as its base. But who knows this?
Not the protein molecules, and certainly not the genes which merely allow their
code to be copied at a certain moment, which moment they do not directly
determine. Perhaps there is some, as yet unknown mechanism; perhaps there is a
circular ring of charges complementary to the charges of the protein molecules
of the first ring at the cell wall. But what would be the origin of this ring of
charges if they do exist? Certainly it would not be any part of the gene code
for the ring proteins. It would have to have been established by a previous gene
(if there is anything to sequential genetic evolution). Does that mean that the
arrival of genes creating the proteins for the flagellum which supposedly
hapenned by 'accidental' mutations was preceded by genes that prepared the way
for this circular form? If that is the case, what is the origin for that
circular set of charges in the cell wall? And what is the genetic antecedent for
that? Are we saying that genes have foreknowledge of future mutations and pave
the way for them by building charging patterns to determine their shapes? How
can genes have foreknowledge of mutations if mutations are accidental, and how
can genes have knowledge of anything if they are simply submicroscopic strings
of nucleic acids?
The cilium is a hairlike shape. The method of
construction is called IFT. These are raft-like proteins that travel up and down
the sides of the cilia carrying new protein building materials in the
construction phase and carrying replacement proteins in the maintenance phase
after the cilium is constructed. On the way down from the tip of the cilium,
these IFT rafts remove no longer needed construction equipment and during the
mature life of the cilium, the IFT remove used up proteins that have been
replaced by fresh ones. The length of the cilia in relation to the rest of the
cell body is crucial to its efficacy. Although Michael Behe explains in great
detail how all the protein material arrives there, he says this regarding the
actual length and breadth of the cilium, "Apparently some as-yet-unknown
switching mechanism senses how much material the cilium needs at any particular
moment and changes the proportion of freight cars (rafts) between
'cargo-capable' amd 'cargo-incapable' as the need arises.'
The
protein motor that powers the IFT rafts to the tip of the cilium (kinesin) is
different than the protein motor that powers the raft on the way back (dynein).
Behe writes, "Exactly what causes IFT to shift from kinesin-powered transport
to dynein transport at the tip of the cilium remains unknown." But that
shift, those rafts reversing direction, is what creates the tip. The exact spot
where those IFT reverse direction determines the length of the cilia. What is it
that the IFT are bumping up against that causes it to change direction? How does
the cilia know exactly how long it needs to be? And what, if anything, does this
have to do with genes?
So we see with the flagellum and the cilium,
although much has been written about their various protein components, their
genetic antecedents and how they are transcribed, translated, folded and
delivered to the construction site at the precise time that they are needed,
nothing is written and nothing is known about how they actually achieve the
exquisite and exquisitely precise shape of cilium and flagellum, which shapes
are the essential factors that enables them to do their work, that enables them,
in fact, to be, cilium and flagellum.
If the shaping of these
microscopic features of single celled creatures cannot be explained by any
genetic mechanism, then how could they have 'evolved.' In the case of the first
flagellum ring, the exact same twenty-six proteins could form any shape. If,
accidentally, they formed a ring some billions of generations ago, there is
nothing in the genetic sequence to distinguish those twenty-six proteins that
formed a ring from those many, many sets of twenty-six that did not. And there
is nothing, directly in the genetic sequence that can guarantee the replication
of that ring once it was accidentally achieved. As I've said before, shape, any
shape, although specified by a genetic sequence is not created by a genetic
sequence. Something else is at work, and that something else is the true
creative power and intelligence behind the construction of living beings. It is
the shapes and the fact that all these shapes are functional that is truly
wonderous. When we see pictures of the developing human embryo, there are
changes in the protein materials, of course, but it is the changes in shape, the
emergence of that human face and human hands and feet and a whole raft of
exquisite and exquisitely functioning internal organs from a seemingly
non-descript collection of cells, that really astonishes us. The genome provides
the necessary materials in the right sequences, but it is the shaper that
creates the human being. Without the shaper all that would be created is an
undifferentiated mass of proteins.
One of the main, if not the main
'proof' of evolution is the repetitive patterns of shapes found throughout the
plant and animal kingdom. This has led evolutionists to conclude that these
commonly shaped traits are homologous; that they have evolved from the same
genetic origin. But on further inspection, many of these seemingly homologous
forms are manufactured by different genes following different embryonic
pathways. In other words, the same shapes repeated over and over, but with
different materials and different means of manufacture. What does this remind us
of from our own world of man-made manufacture? We see, for instance, wheels made
from rubber, from plastic, from iron and wood. We see them appearing in all
different kinds of mechanical settings; all with the same basic shape and
serving the same basic purpose, but used and manufactured in many different
ways. Why is this? Because the wheel is an idea, and machines are created by
combining existing ideas in novel ways.
What I am saying is that the
genome is really an idea for a machine and the construction of that machine, and
each gene is an idea of how to build a smaller sub-machine within that larger
machine. The idea for a machine consists of two parts: the appropriate materials
and the shape that these materials should take. What we have been able to
observe regarding genes is the material part; how genes specify proteins. What
can only be observed by its results is the idea of shape. We see the proteins
manufactured from a genetic code being delivered in the right sequence to a
construction site, and then we see those protein molecules assuming an exquisite
and exquisitely precise shape. But the plan for that shape cannot be seen. Only
the results of that plan can be seen.
Is there an actual, measurable
plan? Some say there is: an energy body, or an astral body that exists prior to
the physical body. This astral body is, supposedly, a subtle pattern of positive
and negative charges that is the plan for all the ideas of shapes and shapes
within shapes connected to that genome. The growing body of multiplying protein
molecules expands along the contours of this astral body, positive to negative
and negative to positive. I am not arguing, at the moment, about whether this is
true or not; or if further research and more delicate instrumentation will
reveal the existence of this astral body. But whether it is true or not, the
next question would be: how did that astral body, or that "plan" get there? How
does an idea on the non-physical plane, in the universal mind, suddenly
translate into a physical body, with or without the intermediary of an energy
body?
Does it seem a little too 'metaphysical' or too weird to you that
an idea could 'magically' translate into a physical reality? But look at
anything and everything that you ever created. Didn't that creation originally
start as an idea? an idea that has no measurable, physical reality; just like
the idea for the design of a building in the mind of the architect? But, you
say, that idea did have a physical reality, an electro-magnetic reality, caused
by the firing of neurons in my brain. But whatever idea you have, whatever
thought or conception, on any topic and any laguage, verbal or non-verbal, it is
associated with the firing of neurons of identical construction which yields a
flow of electrons of identical voltage and deposits of identical chemicals. And
that is true if these ideas or conceptions are taking place in your brain or my
brain. How to explain the amazing sameness of these electrical and chemical
responses with the amazing variety of conceptual stimuli? Isn't it clear then
that neuron firings may be caused by an idea, may be used as a device to record
our ideas, but that they are not the ideas themselves? That we have a thought,
or an idea which leads to the firing of a pattern of neurons which leads to the
stimulus of muscles and speech, which leads to further thoughts and actions,
which leads, ultimately, to the actual manifestation of these ideas on paper or
canvas or wood or clay? Isn't this basically the same process as a cosmic idea
manifesting into an electrical pattern of form (astral body) manifesting into an
actual physical body?
In the last fifty years science has uncovered an
enormous amount of information about the chemical development of life, but
nothing about the development of shape. How could the genome possibly explain,
for instance, the enormously complex and constantly changing shapes and shapes
within shapes of the developing human fetus? The genome of the initial
fertilized egg is identical with the genome in every one of the one hundred
trillion cells of the adult body. Through embryonic development the genome is
replicated first millions, then billions and then trillions of times over,
identically. Yet in each part of the body a different shape is created, and
shapes within shapes, and all these shapes are constantly changing and are
responsible for the functioning of all the various organs and their perfectly
coordinated activities. Doesn't this obviously tell us that their is a central
control, an over arching plan that is somehow connected to the genome, but that
is not created or controlled by the genome?
As I said earlier, the idea
for a machine comes out of a desire to accomplish something and a knowledge of
the obstacles that must be overcome in order to accomplish that. The idea
consists of two parts : the appropriate materials needed and the form that these
materials must take to direct the energy to accomplish the desired task. A gene
involved in the construction of a living body is an idea. The visible part of
this idea is the manufacture and delivery of the appropriate materials
(proteins) in the right sequence (firing pattern). The part that we do not see
directly, but can only see the results of, is the idea of shape. As new proteins
are manufactured and delivered to a construction site, they fill out a shape; a
shape that already exists in the mind of God, or, if you prefer, in the cosmic
consciousness.
Sometimes evolutionary change requires no change in the
genome at all. Witness all the various incarnations of the liver fluke, all done
by firing different genes with different patterns within the same genome. All
that means is that many, many dramatic changes of shape can be wrought using
different arrangements of the same materials. But sometimes a new idea will
require a new material, and then a gene must be added. But a new gene involved
in the construction of a living body can never be just added on. It's much, much
more complicated than that. It must have it's own new delivery system and must
be integrated into the firing patterns of many firing sequences with its own set
of control genes and its own method of being delivered to various construction
sites. The entire organism must be adjusted to accommodate this new gene and new
structure, including adjustments in nerve and muscle connections, in sense of
equilibrium, in the whole real estate of the brain since a new area must be set
up to process information coming from this new structure and going to this new
structure, etc., etc. For humans it would be an amazing,impossible, overwhelming
endeavor. For God, or the Cosmic Conciousness, it may just be what She does.
Are there any hmmmm moments followed by aha moments when the Universal
Mind is creating new structures and, possibly, adding new genes? Who knows?
Perhaps that intelligence is out of time and space and already has the solution
of any environmental problem before it actually occurs. Perhaps it is all
foreseen. I like to think of it otherwise. I like to think of it as the
Universe's loving game. As organisms continue in this process they get more and
more complex and as they do the number of options of things that can be done, by
building on all the existing structures (all the previous ideas) gets narrower
and narrower. But coming up with an amazing solution that involves microscopic
adjustments in gene sequences, firing patterns, metabolism, equilibrium, nerve
and brain function, and still results in a completely integrated being that is
actually more equipped, more able to deal with its environment in new and
interesting ways, a creature that has more options than previously, is, it seems
to me, a loving challenge worthy of the transcendent intelligence of the
Universal Mind.
Going back to the hapless, isolated accidental mutation,
and again I remind you that I am not talking about a mutation in the gene of a
chemical that the body produces, but a mutation in a gene involved in the
construction of the body itself; it should now be clear that such an accident
could never result in anything but damage to the existing structures. There is
no new integration, no new plan, no new firing pattern, and no idea. It is just
a change in a chemical, or in the case of the accidental replication of a
control gene, it may be the replication of a whole extra form, or extra idea
(although it would never mean the creation of a 'new' idea). But that isolated
extra 'idea' like the four winged fruit fly, would be just that: not a new idea
but an isolated, disconnected useless repetition of an already existing idea,
separate from all the myriad interwoven ideas that make up a complex living
organism.
Peace!
Please comment. Your thoughts are always
welcome.